Ventilator Rapid Review

Ultra-fast guide for setting up and troubleshooting the ventilator — covering ~75% of common issues. Three topics:

NOTE

This is a rapid reference — not a comprehensive text. For detailed physiology and advanced modes, consult pulmonary references or the respiratory therapy team.


Setting Up the Vent

Initial Settings (Standard Adult)

ParameterTypical Starting Value
Tidal Volume (Vt)6–8 mL/kg ideal body weight (IBW)
Rate12–16 breaths/min
FiO₂100% → wean to goal SpO₂ ≥ 92%
PEEP5 cm H₂O (start)
I:E Ratio1:2

Initial Settings Check

  1. Confirm ETT placement (CXR, EtCO₂, bilateral breath sounds)
  2. Set alarms: High pressure, low minute ventilation, apnea
  3. Check plateau pressure (goal < 30 cm H₂O) — hold inspiratory hold button

Vent Adjustments

Hypoxia (Low SpO₂)

ProblemIntervention
Low SpO₂FiO₂ first, then ↑ PEEP
Refractory hypoxia↑ PEEP in increments of 2–3 cm H₂O; check plateau pressure
Unilateral lung issueConsider proning, APRV mode, or RT consult

WARNING

If plateau pressure > 30 cm H₂O, consider reducing tidal volume or PEEP. High plateau pressures = ventilator-induced lung injury (VILI) risk.

Hypercapnia (High CO₂ / Low pH)

ProblemIntervention
High CO₂, pH okayRate (minute ventilation)
High CO₂, acidosisRate or ↑ Tidal Volume (check plateau)
Permissive hypercapniaAccept pH ≥ 7.15–7.20 if plateau pressures are a concern

Patient-Ventilator Dyssynchrony

PatternLikely CauseFix
Flow starvationPatient demands more than set flowPeak flow or switch to PC mode
Double-triggeringVt too low for demand↑ Vt or consider PC mode
Auto-PEEP / breath stackingInsufficient expiratory time↓ Rate, ↑ I:E ratio (e.g. 1:3), check for secretions

P/F Ratio for ARDS

Used to stratify ARDS severity and disease progression in place of the A-a gradient.

PaO₂ - From ABG
FiO₂ - From ventilator, HHFNC, or CPAP/BiPAP

ARDS SeverityP/F RatioConsiderations
Mild200 - 300Standard lung-protective ventilation (low Vt)
Moderate100 - 200Consider higher PEEP
Severe< 100Consider proning and paralyizing

Weaning & SBT

TIP

SPH has an excellent SBT and weaning/extubation protocol already in place. See Extubation Readiness Assessment and existing extubation workflows.

Readiness Criteria

  • Cause of respiratory failure resolving
  • Hemodynamically stable (no/minimal vasopressors)
  • Adequate oxygenation: PF Ration (PaO₂ / FiO₂) ≥ 150–200, PEEP ≤ 8
  • Awake, following commands, intact airway reflexes
  • No significant acidosis

SBT Settings

ParameterValue
ModePSV (Pressure Support Ventilation) or T-piece
PS5–8 cm H₂O (if PSV mode)
PEEP5-8 cm H₂O
Duration30–120 minutes

Failure Criteria During SBT

  • RR > 35
  • SpO₂ < 88–90%
  • HR > 140 or new arrhythmia
  • SBP > 180 or < 80
  • Agitation, diaphoresis, accessory muscle use
  • PaCO₂ ↑ > 10 from baseline

Troubleshooting Quick Reference

Alarm / IssueFirst Action
High PressureCheck for secretions/biting/kinked tube → suction → consider bronchodilator
Low Pressure / Low TVCheck circuit disconnection, leak, or cuff leak → re-secure airway
ApneaIncrease back-up rate or change mode
Auto-PEEPIncrease expiratory time → ↓ rate or I:E ratio

Key Reference